Mechanism study on stability enhancement of adefovir dipivoxil by cocrystallization: Degradation kinetics and structure-stability correlation
نویسندگان
چکیده
منابع مشابه
Physicochemical evaluation, study of stability and drug release kinetics from
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A simple and reliable stability-indicating RP-HPLC method was developed and validated for analysis of adefovir dipivoxil (ADV).The chromatographic separation was performed on a C18 column using a mixture of acetonitrile-citrate buffer (10 mM at pH 5.2) 36:64 (%v/v) as mobile phase, at a flow rate of 1.5 ml/min. Detection was carried out at 260 nm and a sharp peak was obtained for ADV at a reten...
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutical Sciences
سال: 2016
ISSN: 0928-0987
DOI: 10.1016/j.ejps.2015.10.006